An Accessible Test Is (Finally, Actually) Available

Posted by Chelsea Belle | Sep 4, 2021 | Prions | 0 |

The blood test prion lab is now available to receive blood samples. 12 testing slots are available.

If you are a practitioner suspecting your patient may have spike-related prion disease, please reach out to be considered to submit a sample. 🧟‍♂️

— Adam Gaertner 🇺🇸 (@veryvirology) September 4, 2021

Leave a reply Cancel reply

Information

Que sont les prions ? Partie II : coronavirus, ARN messager et prions

Que sont les prions ? Partie II : coronavirus, ARN messager et prions

TRIBUNE Santé - Seconde partie de l'article "Que sont les prions ?", étudiant le cas du co...

UVB light at 290nm, which reaches the Earth's surface from the Sun, appears to disable prion protein.

This may mean that the risk of outdoor prion fomite transmission is nil.

Thanks @rifi_s

"UV-Light Exposed Prion Protein Fails to Form Amyloid Fibrils"
https://t.co/TGntzYE1HP

— Adam Gaertner 🇺🇸 (@veryvirology) August 30, 2021

Microglia Form Networks That Engulf and Clear Pathogenic α-Synuclein

Microglia Form Networks That Engulf and Clear Pathogenic α-Synuclein

When microglia are exposed to α-synuclein, they establish a network of intercellular conne...

Woman Dies of Rare Brain Disease Within 3 Months of Second Pfizer Shot, Doctor Says Vaccine Could Be Responsible

In an exclusive interview with The Defender, Gianni Cohen said her mother, Cheryl Cohen, d...

COVID-19 Associated with Long-Term Cognitive Dysfunction, Acceleration of Alzheimer’s Symptoms | AAIC 2021

New research reported at AAIC 2021 found associations between COVID-19 and persistent cogn...

Left: Electron microscope image of an unidentified fiber in 💉 blood.

Right: Atomic force microscope image of a prionic amyloid fibril at 2, 6 and 21 days of aggregation.

🤔

Sources: @DrJohnB2 and https://t.co/6yQMLYmESn pic.twitter.com/ONOtowpz4L

— Adam Gaertner 🇺🇸 (@veryvirology) September 21, 2021

"

New study finds COVID-19 can cause changes in brain that mimic Alzheimer's disease

A new study shows that COVID-19 symptoms that some describe as "brain fog" may be caused b...

4) ➡️In all samples, spontaneous amyloid deposits formed after exposure to the Spike protein. pic.twitter.com/0FZfDXQGFx — Nicola Bidoli 🛡🛡🛡 (@BidoliNicola) July 31, 2021

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

SARS-CoV-2 nucleoprotein can trigger α-synuclein amyloid fibril formation

A new study, released as a preprint on the bioRxiv* server, casts some light on the pathog...

Amyloidosis - Symptoms and causes

http://www.cnrs.fr/en/node/5908

Interesting study providing a difference in prion infectiousness dependent on log concentration. Need a model to extrapolate to levels of spike exposure to predict potential rates of prion disease to occur from SARS-CoV-2 spike exposure. https://t.co/QNvGLxIzrA — COVIDCandy (@covidcandy) July 26, 2021

Last tweet about prions, I had 10 anecdotes. Since that thread, I now have 25 people&carers reporting the same pattern. I am writing a case series on these widespread reports of prion disease. Know someone that sharply declined ~2 weeks after the 💉 with 🧠 issues? Speak up: 👇 — Adam Gaertner 🇺🇸🇺🇸🇺🇸 (@veryvirology) July 18, 2021

More indications of prionic activity of SARS-CoV-2 ... "SARS-CoV-2 activates ER stress and Unfolded protein response" https://t.co/mRIfUUzfX0 Related: https://t.co/Pd8jQumwpA pic.twitter.com/7nc6dEJL1H — COVIDCandy (@covidcandy) July 24, 2021

SARS-CoV-2 Prion-Like Domains in Spike Proteins Enable Higher Affinity to ACE2

SARS-CoV-2 Prion-Like Domains in Spike Proteins Enable Higher Affinity to ACE2

Currently, the world is struggling with the coronavirus disease 2019 (COVID-19) pandemic, ...

SARS-CoV-2 spike protein interactions with amyloidogenic proteins: Potential clues to neurodegeneration

The post-infection of COVID-19 includes a myriad of neurologic symptoms including neurodeg...

Articles Inpress Articles | Journal of Medical - Clinical Research & Reviews | SciVision Publishers

Dr. Fleming on prion domains and CJD from SARS-CoV-2 spike. https://t.co/5rUYZaZQv3 — Adam Gaertner 🇺🇸🇺🇸🇺🇸 (@veryvirology) July 19, 2021

COVID-19 RNA Based Vaccines and the Risk of Prion Disease | Principia Scientific Intl.

Vaccines have been found to cause a host of chronic, late developing adverse events. Some ...

SARS-CoV-2 spike protein interactions with amyloidogenic proteins: Potential clues to neurodegeneration

The post-infection of COVID-19 includes a myriad of neurologic symptoms including neurodeg...

Prions: Beyond a Single Protein

Since the term protein was first coined in 1838 and protein was discovered to be the essen...

CBC News/Radio-Canada distributing 50,000 postcards to learn more about mystery illness

Mystery disease takes life of a North Pole leader

Mystery disease takes life of a North Pole leader

McCoy died this summer, two weeks after doctors diagnosed him with Creutzfeldt-Jakob Disea...

Zombie Preparedness | CDC

Learn about the CDC Center for Preparedness and Response’s zombie preparedness messages an...

It is critical for people to understand information about the Drugs being used for Vaccines including Novavax. Here is how Novavax is made. What's being injected is the spike protein and other irritants. It still contains the PRIONs of gp120 & the PLD near receptor binding site. pic.twitter.com/sqcvZk4Uyb — Dr Richard M Fleming (@Doctor_I_am_The) July 9, 2021

There Is No Safe Dose of Prions

There Is No Safe Dose of Prions

Understanding the circumstances under which exposure to transmissible spongiform encephalo...

Visual Disturbances and Headache as Presenting Symptoms of... : Journal of Neuro-Ophthalmology

An abstract is unavailable. This article is available as a PDF only.

Worse Than the Disease? Reviewing Some Possible Unintended Consequences of the mRNA Vaccines Against COVID-19 | International Journal of Vaccine Theory, Practice, and Research

Creutzfeldt-Jakob disease in a man with COVID-19: SARS-CoV-2-accelerated neurodegeneration?

We describe a man whose first manifestations of Creutzfeldt-Jakob disease occurred in tand...

Potential Treatments

*Please note that nothing here should be considered to be medical advice. Please speak to your doctor.

Quercetin Disaggregates Prion Fibrils and Decreases Fibril-Induced Cytotoxicity and Oxidative Stress

Transmissible spongiform encephalopathies (TSEs) are fatal neurodegenerative diseases caus...

The Potential of Serratiopetidase and Lumbrokinase for the Degradation of Prion Peptide 106-126 - an In Vitro and In Silico Perspective - PubMed

The Potential of Serratiopetidase and Lumbrokinase for the Degradation of Prion Peptide 106-126 - an In Vitro and In Silico Perspective - PubMed

Finally, the toxicity of the disintegrated amyloids was assessed using PC12 cell lines whi...

Binding of methylene blue to a surface cleft inhibits the oligomerization and fibrillization of prion protein - PubMed

Binding of methylene blue to a surface cleft inhibits the oligomerization and fibrillization of prion protein - PubMed

Neurodegenerative protein misfolding diseases, including prionopathies, share the common f...

Induced dural lymphangiogenesis facilities soluble amyloid-beta clearance from brain in a transgenic mouse model of Alzheimer's disease - PubMed

Induced dural lymphangiogenesis facilities soluble amyloid-beta clearance from brain in a transgenic mouse model of Alzheimer's disease - PubMed

Impaired amyloid-β clearance from the brain is a core pathological event in Alzheimer's di...

Artemisinin B Improves Learning and Memory Impairment in AD Dementia Mice by Suppressing Neuroinflammation | Request PDF

Artemisinin B Improves Learning and Memory Impairment in AD Dementia Mice by Suppressing Neuroinflammation | Request PDF

Request PDF | Artemisinin B Improves Learning and Memory Impairment in AD Dementia Mice by...

Lactoferrin protects against prion protein-induced cell death in neuronal cells by preventing mitochondrial dysfunction - PubMed

Lactoferrin protects against prion protein-induced cell death in neuronal cells by preventing mitochondrial dysfunction - PubMed

Prion disorder-related neurodegenerative diseases are characterized by the accumulation of...

Pomegranate seed oil nanoemulsions for the prevention and treatment of neurodegenerative diseases: the case of genetic CJD - PubMed

Pomegranate seed oil nanoemulsions for the prevention and treatment of neurodegenerative diseases: the case of genetic CJD - PubMed

This team of authors report that a nanoformulation of pomegranade seed oil, containing hig...

Inactivation of Prions and Amyloid Seeds with Hypochlorous Acid

Author Summary Many serious diseases have been linked to pathogenic states of various prot...

Multiple mechanisms of age-dependent accumulation of amyloid beta protein in rat brain: Prevention by dietary supplementation with N-acetylcysteine, α-lipoic acid and α-tocopherol - PubMed

Multiple mechanisms of age-dependent accumulation of amyloid beta protein in rat brain: Prevention by dietary supplementation with N-acetylcysteine, α-lipoic acid and α-tocopherol - PubMed

The aged brain may be used as a tool to investigate altered metabolism of amyloid beta pro...

Intracellular re-routing of prion protein prevents propagation of PrPSc and delays onset of prion disease

Prion diseases are fatal and transmissible neurodegenerative disorders linked to an aberra...

Vitamin D2 interacts with Human PrPc (90–231) and breaks PrPc oligomerization in vitro

PrP[sc] , the pathogenic isoform of PrP[c] , can convert PrP[c] into PrP[sc] through direc...

Mefloquine, an Antimalaria Drug with Antiprion Activity In Vitro, Lacks Activity In Vivo

In view of the effectiveness of antimalaria drugs inhibiting abnormal protease-resistant p...

The curious antiprion activity of antimalarial quinolines

A series of antimalarial quinoline compounds potently inhibit prion accumulation in cell c...

https://www.sciencedaily.com/releases/2006/10/061030120759.htm

Molecular chaperone slows prion disease

Tested in mice and macaques, MC tamps down neurodegeneration

Neuronal death induced by misfolded prion protein is due to NAD+ depletion and can be relieved in vitro and in vivo by NAD+ replenishment

The mechanisms of neuronal death in protein misfolding neurodegenerative diseases such as ...

Degradation of the disease-associated prion protein by a serine protease from lichens - PubMed

Degradation of the disease-associated prion protein by a serine protease from lichens - PubMed

The disease-associated prion protein (PrP(TSE)), the probable etiological agent of the tra...

https://www.nature.com/articles/nature.2016.20509

Normal prions as a new target of cobalamin (vitamin B12) in rat central nervous system - PubMed

Normal prions as a new target of cobalamin (vitamin B12) in rat central nervous system - PubMed

The pathogenesis of cobalamin (Cbl)-deficient (Cbl-D) neuropathy and the role of normal pr...

Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-κB and AP-1 Activation - PubMed

Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-κB and AP-1 Activation - PubMed

Over activation of microglia results in the production of proinflammatory agents that have...

Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity - PubMed

Autophagy induced by resveratrol prevents human prion protein-mediated neurotoxicity - PubMed

Our previous study revealed that resveratrol blocks prion protein peptide PrP(106-126)-ind...